Internship Regenerative Orthopaedics ( 1 year contract)

von: AO Foundation | Ort: Davos Platz
N: AOFoundation
Job Description

Join our research team at AO Research Institute Davos (ARI) for a 12-months internship! Contribute actively to a SNSF funded project investigating interplay between biomaterials and immune cells. Apply now!

 
Tissue regeneration and homeostasis after injury or biomaterial implantation are controlled by a spectrum of components of the immune system and their mutual regulation. The initial immune response at the site of inflammation is led by neutrophils, which are the first responders to be recruited and as such orchestrate the progression of the subsequent inflammatory events after implantation.

Goal:
In this project, we will study the effect of different surface topographies on behaviour of neutrophils and peripheral blood monocytes derived macrophages, and to find out the how sequential exposure of neutrophils and macrophages influences the differentiation of mesenchymal stromal cells (MSCs) and healing response. With this investigation we will create an in vitro platform to better understand how different players of the immune system contribute to interacting with biomaterials and, to test the role of immune signalling on MSC differentiation. Gaining a deeper understanding in the complex interplay between the innate immune cells and MSCs will allow us to develop platforms for assessing the immunomodulatory properties of the materials.

Job Requirements

– Bachelor's or Master's degree in a relevant field (biology, biochemistry, immunology, materials science, biomedical engineering etc.)
– Analyze experimental data using appropriate statistical methods and contribute to the interpretation of results.
– Ability to work both independently and collaboratively in a team environment.
– Participate in regular project meetings and contribute to the overall progress of the research.
– Willing to be in the office/laboratory on a daily basis 

 

 

 

Working for us, you can expect:

  • An interesting and varied job in an exciting and innovative organization
  • The opportunity to be part of a highly committed international team
  • Modern infrastructure
  • Employment conditions which match the requirements and offer a high degree of flexibility regarding working hours and location

N: AOFoundation

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